Green Tea Consumption : Reduce Risk of Cancer Development

The consumption of green tea has long been associated with a reduced risk of cancer development. Tea beverages are brewed from the Camellia sinensis plant (leaves) and have been consumed in China for nearly 5000 years. Of the total amount of tea undergone different manufacturing processes produced and consumed globally, 78% is black tea, 20% is green tea, and <2% is oolong tea. Learn How to Healing Cancer Yourself


Black tea is consumed primarily in Western and some Asian countries, whereas green tea is consumed primarily in China, Japan, India, and a few countries in North Africa and the Middle East. The production
and consumption of oolong tea and pu-erh tea are confined to southeastern China and Taiwan.

In recent years, many studies from our and other laboratories have shown that green tea, oolong tea, black tea and pu-erh tea contains several tea catechin components; the major catechins in tea are epicatechin (EC), epicatechin-3-gallate (ECG), epigallocatechin (EGC), and epigallocatechin-3-gallate (EGCG)

Epicatechin-3-gallate (ECG) or-epigallocatechin-3-gallate (EGCG) are the major antioxidative polyphenolic compounds of green tea. They have been shown to exert growth-inhibitory potential of various cancer cells in culture and antitumor activity in vivo models. ECG or EGCG could interact with various molecules like proteins, transcription factors, and enzymes, which block multiple stages of carcinogenesis via regulating intracellular signaling transduction pathways.

Moreover, ECG and EGCG possess pharmacological and physiological properties including induction of phase II enzymes, mediation of anti-inflammation response, regulation of cell proliferation and apoptosis effects and prevention of tumor angiogenesis, invasion and metastasis. Numerous review articles have been
focused on EGCG, however none have been focused on ECG despite many studies supporting the cancer preventive potential of ECG. To develop ECG as an anticarcinogenic agent, more clear understanding of the cell signaling pathways and the molecular targets responsible for chemopreventive and chemotherapeutic effects are needed.

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