Migraine Patients Tend to Have Abnormal Brain Structur

More than 300 million people around the world have an intense migraine, i.e. a throbbing headache often accompanied by nausea, light sensitivity and changes in the function of visual or sensory. Recent studies indicate that migraine patients have a specific part of the brain that are abnormal.
Previous research shows that there is shrinkage or atrophy of regions of the cortex of the brain in patients of migraine. It is associated with the processing of pain, which may occur due to chronic stimulation on the area.  I
The latest study, scientists in Italy studying the cortical thickness and surface area of the cerebral cortex of migraine patients. Researchers found that some of the migraine patients tend to have abnormalities of the brain at birth.

The study was led by Dr. Massimo Filippi, Director of Neuroimaging Research Unit at the Ospedale San Raffaele University and professor of Neurology at the University Vita-Salute's San Raffaele Scientific Institute in Milan, who want to understand the basic pathophysiology of neurological diseases, including migraine using neuroimaging technology.

Filippi began his research several years ago by studying migraine patients with MRI to determine structural and functional abnormalities associated with migraine, the goal is to identify the mechanisms that cause clinical expression and monitor its evolution.

"Patients with migraine was not only just have brain function differently, but in fact may have structural differences in the brains of people who are also healthy," Filippi said.

The study involved 62 adults with migraine and 18 healthy people. The findings, were published online on March 26 in the journal Radiology.

Based on the results of the MRI scan, the team found that the patient's brain with migraines quite complicated. Some areas of the cortex in the brain of migraine patients seem thicker, but some other areas of the cortex is thinner. The thickness of cortex in patients of migraine is uneven when compared to the brains of healthy people.

Filippi stated that it is important to understand the structural changes in the brain associated with migraine because it can give an idea about the cause of pain and other symptoms. For example, doctors may be able to monitor the structural changes in the brain cortex of migraine patients to measure response to treatment.

Researchers have yet to determine whether structural changes in the brain is dynamic or continue to change over time. The research team is now still follow the research participants to see if the structural patern in the btarin is ' stable ' or tend to shift,  and it will develop the research of migraine to children.


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